2. Leukemia Cutis
Leukemia cutis occurs when leukemia cells infiltrate the skin. It typically presents as firm papules, plaques, or nodules that may appear violet, red-brown, or flesh-colored, says Dr. Chaer. On darker skin tones it may appear dark purple, grayish, or hyperpigmented.
Brittany Dulmage, MD, a board-certified dermatologist who specializes in oncodermatology at The Ohio State University Wexner Medical Center in Columbus, notes that the rash typically appears as raised bumps that may appear red or purple in color on lighter skin tones.
“Leukemia cutis can develop before or alongside systemic leukemia and often signals active or relapsed disease,” says Chaer. It is most common in children born with congenital leukemia, a rare condition that starts within the first month of life; leukemia cutis is estimated to affect about 25 to 30 percent of children with congenital leukemia.
Treatment focuses on managing the underlying leukemia rather than the skin alone, Chaer says.
3. Folliculitis
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